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Filtered Search Results
eMolecules 1,4-Diazabicyclo[3.2.2]nonane dihydrochloride | 150208-70-1 | MFCD07618268 | 1g
Combi-Blocks | 1,4-Diazabicyclo[3.2.2]nonane dihydrochloride | 1g | 232314883 | QB-0225 | 97.000 | 150208-70-1 | MFCD07618268 | 199.120 | C7H16Cl2N2
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eMolecules 1803599-47-4 | ChemScene | NN-Dimethylpiperidine-3-sulfonamide hydrochloride | 100mg | 712840124 | CS-0434889 | MFCD28397455 | 228.74 | C7H17ClN2O2S
Ambeed | Boc-D-Abu-OH.DCHA | 100g | 599120104 | A831164 | 27494-47-9 | MFCD00235886 | 384.561 | C21H40N2O4
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eMolecules 74274-01-4 | 2-Quinolin-2-yl-ethylamine dihydrochloride | J & W PharmLab LLC | MFCD11109969 | 245.150 | C11H14Cl2N2 | 96.000 | Cl.Cl.NCCc1ccc2ccccc2n1 | 5g | 289356798
2-Quinolin-2-yl-ethylamine dihydrochloride | J & W PharmLab LLC | 74274-01-4 | MFCD11109969 | 245.150 | C11H14Cl2N2 | 96.000 | Cl.Cl.NCCc1ccc2ccccc2n1 | 5g | 289356798
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eMolecules 50678-87-0 | 1-Isopropylpiperidine-3-carboxylic acid hydrochloride | Combi-Blocks | MFCD06800892 | 207.700 | C9H18ClNO2 | 96.000 | Cl.CC(C)N1CCCC(C1)C(O)=O | 5g | 388719112
1-Isopropylpiperidine-3-carboxylic acid hydrochloride | Combi-Blocks | 50678-87-0 | MFCD06800892 | 207.700 | C9H18ClNO2 | 96.000 | Cl.CC(C)N1CCCC(C1)C(O)=O | 5g | 388719112
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Chemie Tek RMC-6291 covalent inhibitor 5mg
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RMC-6291 is an orally bioavailable, covalent inhibitor of the active, guanosine triphosphate (GTP)-bound form of the oncogenic KRAS substitution mutation G12C, KRASG12C(ON). RMC-6291 forms a tri-complex with the intracellular chaperone protein and immunophilin cyclophilin A (CypA) and KRASG12C(ON). This tri-complex blocks KRASG12C(ON)-mediated signaling. RMC-6291 elicits deep and durable suppression on RAS pathway activity in KRASG12C tumor models (refs 1, 2).
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Sigma Aldrich Fine Chemicals Biosciences Spermine tetrahydrochloride BioReagent, for molecular biology | 306-67-2 | MFCD00012914 | 5G
Spermine tetrahydrochloride BioReagent, for molecular biology | Mol Wt: 348.18 | 306-67-2 | MFCD00012914 | 5G
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eMolecules Nb-Azido-L-2,3-diaminopropionic acid hydrochloride | Chem-ImpexMFCD01674173 | 130.107 | C3H6N4O2 | 88.000 | NC(CN=[N+]=[N-])C(O)=O | 1g | 322125772
Nb-Azido-L-2,3-diaminopropionic acid hydrochloride | Chem-ImpexMFCD01674173 | 130.107 | C3H6N4O2 | 88.000 | NC(CN=[N+]=[N-])C(O)=O | 1g | 322125772
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Medchemexpress LLC RP-1664 | 2980682-00-4 | 98.77% | 514.55 | 50 MG
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RP-1664 is a selective and orally active PLK4 inhibitor with an IC50 of 3 nM. It demonstrates exquisite selectivity over related kinases, including AURKA/B and PLK1. It disrupts centriole biogenesis in cancer cells, leading to an accumulation of PLK4 and p21 protein. It shows increased sensitivity in TRIM37-high-expressing cells or tumors and exhibits anti-tumor activity in breast cancer and neuroblastoma research.
- Selective and orally active PLK4 inhibitor.
- IC50 of 3 nM for PLK4.
- Exquisite selectivity over AURKA/B and PLK1.
- Disrupts centriole biogenesis in cancer cells.
- Leads to accumulation of PLK4 and p21 protein.
- Increased sensitivity in TRIM37-high-expressing cells or tumors.
- Exhibits anti-tumor activity in breast cancer and neuroblastoma research.
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Aobchem AOBCHEM
5000937737 4-ETHOXY-2-METHYLPHENYL PHEN
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Aobchem AOBCHEM
5000937793 4-ETHOXY-2-METHYLPHENYL PHEN
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Medchemexpress LLC RP-1664 | 2980682-00-4 | 98.8% | 514.55 | 25 MG
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RP-1664 is a selective and orally active PLK4 inhibitor with an IC50 of 3 nM. It demonstrates high selectivity over related kinases like AURKA/B and PLK1. This compound disrupts centriole biogenesis in cancer cells, leading to an accumulation of PLK4 and p21 protein. RP-1664 shows increased sensitivity in TRIM37-high-expressing cells or tumors and exhibits anti-tumor activity in breast cancer and neuroblastoma research.
- Selective and orally active PLK4 inhibitor.
- IC50 of 3 nM for PLK4.
- Exhibits exquisite selectivity over related kinases such as AURKA/B and PLK1.
- Disrupts centriole biogenesis in cancer cells.
- Leads to accumulation of PLK4 and p21 protein.
- Demonstrates increased sensitivity in TRIM37-high-expressing cells or tumors.
- Exhibits anti-tumor activity in breast cancer and neuroblastoma research.
- Appearance: Solid, White to off-white.
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Aobchem AOBCHEM
5000874778 2- 2- 2 2-DIMETHYLPROPOXY PHEN
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Medchemexpress LLC 2 2-DIMETHOXY-2-PHEN 500G
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5000205961 2 2-DIMETHOXY-2-PHEN 500G
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Aobchem AOBCHEM
5000908912 4-ETHOXY-3-METHYLPHENYL PHEN
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Aobchem AOBCHEM
5000917660 5- TRIFLUOROMETHOXY -1 3-PHEN
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